Determinants of renal recovery and mortality inpatients undergoing continuous renal replacement therapy in the ICU

Methods Electronic medical records of patients requiring CRRT during their stay in our 35-bed medical-surgical ICU (January 2012-December 2013) were reviewed. Patients were excluded if they were dialysis-dependent prior to admission, started on CRRT for toxin removal only, transferred to another hospital while on CRRT or died within 24 hours of admission. Binary logistic regression was performed to identify independent variables significantly associated with mortality and renal recovery after adjusting for age, gender, APACHE II score and chronological time to starting CRRT. Creatinine, net fluid balance and ultrafiltration were adjusted for weight; serum urea was adjusted for gastro-intestinal bleeding and steroid use.